The global healthcare ecosystem is in chaos, caught in the convergence of pandemic-induced disruption, residual inequities, burnout, and turnover. Nurse Leaders can either succumb to the churn or spot – and seize – a rare opportunity for true transformation They must thoughtfully consider all aspects of their traditional roles and tackle trigger topics such as staffing, scheduling, value-based care, outcome tracking, and more. Informed, empowered nurses can re-envision roles, integrate technologies, and develop new models to deliver the highest level of patient care.